SPRO
Spero Therapeutics, Inc.
NASDAQ · Healthcare · Biotechnology · US
$1.13
+0.89%0
Insider buys (3m)
0
Insider sells (3m)
$0.00
Net value (3m)
-49.3%
Price return (3m)
Form 4 filings
| Date | Insider | Activity | Shares | Price |
|---|---|---|---|---|
| Aug 6, 2026 | Zack Debra · officer: Chief Medical Officer | A-Award | 162,311 | $0.00 |
| Aug 6, 2026 | Zack Debra · officer: Chief Medical Officer | A-Award | 324,675 | $1.54 |
| Jun 25, 2026 | Smith Cynthia · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | Tregoning Kathleen · director | A-Award | 20,000 | $2.15 |
| Jun 25, 2026 | Tregoning Kathleen · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | Deshpande Milind · director | A-Award | 20,000 | $2.15 |
| Jun 25, 2026 | Deshpande Milind · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | VINK PATRICK V.J.J. · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | Smith Cynthia · director | A-Award | 20,000 | $2.15 |
| Jun 25, 2026 | Pottage John C Jr · director | A-Award | 20,000 | $2.15 |
| Jun 25, 2026 | Pottage John C Jr · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | Jackson Scott Thomas · director | A-Award | 20,000 | $2.15 |
| Jun 25, 2026 | Jackson Scott Thomas · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | THOMAS FRANK E · director | A-Award | 20,000 | $2.15 |
| Jun 25, 2026 | THOMAS FRANK E · director | A-Award | 10,000 | $0.00 |
| Jun 25, 2026 | VINK PATRICK V.J.J. · director | A-Award | 20,000 | $2.15 |
| May 6, 2026 | Rajavelu Esther · officer: See Remarks | Sale | 25,240 | $2.51 |
| Feb 9, 2026 | Keutzer Timothy · officer: Chief Operating Officer | Sale | 18,652 | $2.36 |
| Feb 9, 2026 | Rajavelu Esther · officer: See Remarks | Sale | 50,816 | $2.36 |
| Feb 9, 2026 | Rajavelu Esther · officer: See Remarks | Sale | 37,101 | $2.36 |
| Feb 5, 2026 | Keutzer Timothy · officer: Chief Operating Officer | Sale | 3,471 | $2.24 |
| Feb 5, 2026 | Keutzer Timothy · officer: Chief Operating Officer | A-Award | 68,000 | $0.00 |
| Feb 5, 2026 | Keutzer Timothy · officer: Chief Operating Officer | Sale | 18,891 | $2.20 |
| Feb 5, 2026 | Keutzer Timothy · officer: Chief Operating Officer | Sale | 24,224 | $2.14 |
| Feb 5, 2026 | Keutzer Timothy · officer: Chief Operating Officer | A-Award | 137,000 | $2.23 |
| Feb 4, 2026 | Rajavelu Esther · officer: See Remarks | Sale | 18,442 | $2.20 |
| Feb 4, 2026 | Rajavelu Esther · officer: See Remarks | A-Award | 249,000 | $0.00 |
| Feb 4, 2026 | Rajavelu Esther · officer: See Remarks | A-Award | 498,000 | $2.23 |
| Nov 12, 2025 | Rajavelu Esther · officer: See Remarks | Sale | 40,270 | $2.37 |
| Sep 3, 2025 | Keutzer Timothy · officer: Chief Operating Officer | Sale | 1,695 | $1.97 |
Institutional positioning
13F filings over the trailing two quarters
New 30Increased 28Reduced 18Sold out 11
| Filer | Action | Shares | Filed |
|---|---|---|---|
| GSK PLC | Unchanged | 9,190,606 | May 14, 2026 |
| GSK plc | Unchanged | 9,190,606 | Aug 13, 2026 |
| PFIZER INC | Unchanged | 2,362,348 | May 12, 2026 |
| PFIZER INC | Unchanged | 2,362,348 | Aug 13, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 2,036,226 | Aug 13, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | New Position | 1,799,880 | May 15, 2026 |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | 1,189,235 | May 14, 2026 |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | 947,904 | Aug 13, 2026 |
| Alphabet Inc. | Unchanged | 889,979 | Aug 7, 2026 |
| ALPHABET INC. | Unchanged | 889,979 | May 8, 2026 |
| TWO SIGMA INVESTMENTS, LP | Increased | 885,631 | May 15, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Increased | 807,590 | Aug 14, 2026 |
| BlackRock, Inc. | Increased | 594,404 | Aug 7, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 566,329 | Aug 12, 2026 |
| RAYMOND JAMES FINANCIAL INC | New Position | 521,705 | Aug 14, 2026 |
Insider activity from SEC Form 4; institutional positioning from 13F filings · Latest filing Aug 6, 2026