SION
Sionna Therapeutics, Inc.
NASDAQ · Healthcare · Biotechnology · US
$5.96
−16.99%Price chart
Aug 19Aug 24Aug 27Sep 1Sep 4Sep 10Sep 15Sep 18
Key dataSep 18, 2026
Open$7.14
From 52W high−88.32%
Volume3.67M
Market cap$269.47M
P/E (TTM)—
P/S (TTM)—
Div yield—
Key dataSep 18, 2026
Open
$7.14
From 52W high
−88.32%
Volume
3.67M
Market cap
$269.47M
ValuationView details →
P/E (Fwd)
—
EV/EBITDA
−0.7x
P/E (TTM)
—
RSI (14)
30.4
MomentumView details →
1D Return
−16.99%
YTD Return
−84.19%
SummaryUpdated Jun 1, 2026
Sionna Therapeutics, Inc. (NASDAQ:SION) is a clinical-stage biopharmaceutical company founded to develop innovative treatments for cystic fibrosis patients. The company emerged from stealth mode and went public, focusing specifically on creating medicines that restore normal function to the defective protein responsible for cystic fibrosis. Sionna represents a specialized player in the rare disease therapeutics space, dedicating its resources entirely to addressing the underlying molecular defects that cause cystic fibrosis rather than just managing symptoms.
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Latest newsMore news →
Sionna Therapeutics announced it will cut its workforce by 46% after SION-719 failed a key cystic fibrosis study, shifting focus to SION-451 and SION-2222.4d agoSionna Therapeutics announced role changes effective September 16, 2026, for Chief Medical Officer Charlotte McKee, Chief Financial Officer Elena Ridloff, and Chief Legal Officer Jennifer Fitzpatrick.6d agoSionna Therapeutics terminated Chief Business Officer Caroline Stark Beer effective September 15, 2026, with Elena Ridloff succeeding her.6d ago