Sionna Therapeutics, Inc. (SION) Insider Trading

Over the last 3 months, SION insiders made 0 open-market buys and 5 sales, a net sale of -$18.7M (SEC Form 4). Over the last 6 months, 41 institutions increased and 30 reduced their position (13F).

Insider Activity

Sentiment
0/100
Buys (3m)
0
Sells (3m)
5
Net (3m)
-$18.7M
Insider trades by month Buys Sells
Jan
Feb
Mar
Apr
May
Jul
Context3-month price -85.6%Institutions reducing (13F)
DateInsiderTypeSharesPrice
Jul 9, 2026Thompson Peter A.directorSell85,918$44.86
Jul 9, 2026ORBIMED ADVISORS LLCdirectorSell85,918$44.86
Jul 7, 2026Fitzpatrick Jenniferofficer: Chief Legal OfficerSell10,250$43.60
Jul 7, 2026Fitzpatrick Jenniferofficer: Chief Legal OfficerOption10,250$6.11
Jul 2, 2026Thompson Peter A.directorSell115,844$45.50
Jul 2, 2026ORBIMED ADVISORS LLCdirectorSell115,844$45.50
Jun 18, 2026Stelzer LauriedirectorGrant17,340$36.73
Jun 18, 2026Thompson Peter A.directorGrant17,340$36.73
Jun 18, 2026Viney Joanne L.directorGrant17,340$36.73
Jun 18, 2026RA CAPITAL MANAGEMENT, L.P.director, 10 percent owner: Grant17,340$36.73
Jun 18, 2026Booth BrucedirectorGrant17,340$36.73
Jun 18, 2026Clancy Paul JdirectorGrant17,340$36.73
Jun 18, 2026Resnick JoshuadirectorGrant17,340$36.73
Jun 18, 2026Fleming Harold EdwarddirectorGrant17,340$36.73
Jun 18, 2026Ruddy Marcella K.directorGrant17,340$36.73
May 29, 2026ORBIMED ADVISORS LLCdirectorSell101$44.49
May 29, 2026Thompson Peter A.directorSell101$44.49
May 11, 2026Thompson Peter A.directorSell48,546$44.61
May 11, 2026ORBIMED ADVISORS LLCdirectorSell184,639$46.22
May 11, 2026ORBIMED ADVISORS LLCdirectorSell59,767$44.58
May 11, 2026ORBIMED ADVISORS LLCdirectorSell48,546$44.61
May 11, 2026Thompson Peter A.directorSell184,639$46.22
May 11, 2026Thompson Peter A.directorSell59,767$44.58
Apr 21, 2026ORBIMED ADVISORS LLCdirectorSell2,948$44.52
Apr 21, 2026Thompson Peter A.directorSell52,397$44.68
Apr 21, 2026Thompson Peter A.directorSell2,948$44.52
Apr 21, 2026ORBIMED ADVISORS LLCdirectorSell52,397$44.68
Apr 16, 2026ORBIMED ADVISORS LLCdirectorSell47,814$44.51
Apr 16, 2026ORBIMED ADVISORS LLCdirectorSell235,863$44.64
Apr 16, 2026Thompson Peter A.directorSell47,814$44.51

Source: SION SEC Form 4 filings, latest Jul 9, 2026. For informational purposes only — not investment advice.

Institutional activity (13F)

How institutions changed their SION positions over the last 6 months (SEC Form 13F).

Increased
41
New positions
33
Reduced
30
Sold out
120
Largest moves
InstitutionActionSharesFiled
RA CAPITAL MANAGEMENT, L.P.Unchanged9.9MMay 15, 2026
TPG GP A, LLCReduced6.5MMay 15, 2026
ORBIMED ADVISORS LLCReduced3.5MMay 15, 2026
VIKING GLOBAL INVESTORS LPUnchanged3.2MMay 15, 2026
ATLAS VENTURE LIFE SCIENCE ADVISORS, LLCUnchanged3.0MMay 14, 2026
ENAVATE SCIENCES GP, LLCUnchanged2.5MMay 15, 2026
JPMORGAN CHASE & COIncreased1.5MMay 13, 2026
JENNISON ASSOCIATES LLCIncreased1.5MMay 6, 2026
BLACKROCK, INC.Increased1.3MMay 13, 2026
CITADEL ADVISORS LLCIncreased1.2MMay 15, 2026
VANGUARD CAPITAL MANAGEMENT LLCNew Position1.0MMay 15, 2026
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)Unchanged971KMay 15, 2026
PRICE T ROWE ASSOCIATES INC /MD/Reduced756KMay 15, 2026
STATE STREET CORPIncreased756KMay 15, 2026
PERCEPTIVE ADVISORS LLCReduced658KMay 29, 2026

Source: SEC Form 13F filings. For informational purposes only — not investment advice.