Madrigal Pharmaceuticals, Inc. (MDGL) Insider Trading
Over the last 3 months, MDGL insiders made 0 open-market buys and 11 sales, a net sale of -$1.7M (SEC Form 4). Over the last 6 months, 272 institutions increased and 272 reduced their position (13F).
Insider Activity
Sentiment
0/100
Buys (3m)
0
Sells (3m)
11
Net (3m)
-$1.7M
Insider trades by month Buys Sells
Jan
Mar
May
Jun
Jul
Aug
Context3-month price +10.5%Institutions accumulating (13F)
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| Aug 20, 2026 | Kelley Shannon Tofficer: General Counsel | Sell | 664 | $514.97 |
| Aug 18, 2026 | REED JOHN Cdirector | Grant | 647 | — |
| Aug 18, 2026 | REED JOHN Cdirector | Grant | 1,078 | $507.56 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 280 | $555.05 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 269 | $547.08 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 140 | $542.75 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 1 | $550.72 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 153 | $550.01 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 110 | $543.79 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Option | 50,000 | — |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 47 | $548.87 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 545 | $544.71 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 680 | $547.70 |
| Jul 20, 2026 | Sibold William Johndirector, officer: President and CEO | Sell | 275 | $545.71 |
| Jun 18, 2026 | FOUSE JACQUALYN Adirector | Grant | 454 | — |
| Jun 18, 2026 | Brennan Daniel J.director | Grant | 404 | — |
| Jun 18, 2026 | Levy Richard Sdirector | Grant | 454 | — |
| Jun 18, 2026 | Taub Rebeccadirector | Grant | 766 | $499.86 |
| Jun 18, 2026 | Brennan Daniel J.director | Grant | 681 | $499.86 |
| Jun 18, 2026 | Levy Richard Sdirector | Grant | 766 | $499.86 |
| Jun 18, 2026 | BAKER BROS. ADVISORS LPdirector | Grant | 908 | — |
| Jun 18, 2026 | BAKER BROS. ADVISORS LPdirector | Grant | 1,532 | $499.86 |
| Jun 18, 2026 | Daly James Mdirector | Grant | 766 | $499.86 |
| Jun 18, 2026 | Taub Rebeccadirector | Grant | 454 | — |
| Jun 18, 2026 | FOUSE JACQUALYN Adirector | Grant | 766 | $499.86 |
| Jun 18, 2026 | Daly James Mdirector | Grant | 454 | — |
| Jun 1, 2026 | Soergel Davidofficer: Chief Medical Officer | Sell | 1,042 | $495.74 |
| May 22, 2026 | Levy Richard Sdirector | Sell | 657 | $515.92 |
| May 22, 2026 | Levy Richard Sdirector | Sell | 1,497 | $517.59 |
| May 22, 2026 | Levy Richard Sdirector | Sell | 439 | $512.50 |
Source: MDGL SEC Form 4 filings, latest Aug 20, 2026. For informational purposes only — not investment advice.
Institutional activity (13F)
How institutions changed their MDGL positions over the last 6 months (SEC Form 13F).
Increased
272
New positions
144
Reduced
272
Sold out
41
Largest moves
| Institution | Action | Shares | Filed |
|---|---|---|---|
| BAKER BROS. ADVISORS LP | Increased | 2.1M | Aug 14, 2026 |
| BAKER BROS. ADVISORS LP | Unchanged | 2.1M | May 15, 2026 |
| JANUS HENDERSON GROUP PLC | Increased | 2.0M | May 18, 2026 |
| RTW INVESTMENTS, LP | Unchanged | 2.0M | May 15, 2026 |
| RTW INVESTMENTS, LP | Unchanged | 2.0M | Aug 14, 2026 |
| Jupiter Topco LLC | New Position | 1.9M | Aug 14, 2026 |
| Avoro Capital Advisors LLC | Increased | 1.8M | Aug 14, 2026 |
| AVORO CAPITAL ADVISORS LLC | Reduced | 1.8M | May 15, 2026 |
| AVORO CAPITAL ADVISORS LLC | Reduced | 1.8M | Mar 16, 2026 |
| BLACKROCK, INC. | Reduced | 1.6M | May 13, 2026 |
| PAULSON & CO. INC. | Reduced | 1.4M | May 15, 2026 |
| PAULSON & CO. INC. | Reduced | 1.3M | Aug 14, 2026 |
| BlackRock, Inc. | Reduced | 1.2M | Aug 7, 2026 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New Position | 841K | May 8, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 836K | Aug 13, 2026 |
Source: SEC Form 13F filings. For informational purposes only — not investment advice.