Ionis Pharmaceuticals, Inc. (IONS) Insider Trading

Over the last 3 months, IONS insiders made 0 open-market buys and 23 sales, a net sale of -$24.4M (SEC Form 4). Over the last 6 months, 364 institutions increased and 302 reduced their position (13F).

Insider Activity

Sentiment
0/100
Buys (3m)
0
Sells (3m)
23
Net (3m)
-$24.4M
Insider trades by month Buys Sells
Jan
Feb
Mar
Apr
May
Jun
Context3-month price +5.6%Institutions accumulating (13F)
DateInsiderTypeSharesPrice
Jun 30, 2026Schneider Eugeneofficer: EVP, Chf Clinical Develop OfcrOption26,000$60.89
Jun 30, 2026O'NEIL PATRICK R.officer: EVP CLO & General CounselSell3,069$80.00
Jun 30, 2026Schneider Eugeneofficer: EVP, Chf Clinical Develop OfcrSell26,000$81.05
Jun 30, 2026Baroldi Josephofficer: EVP, Chief Business OfficerOption3,866$56.78
Jun 30, 2026Baroldi Josephofficer: EVP, Chief Business OfficerOption1,769$32.60
Jun 30, 2026Baroldi Josephofficer: EVP, Chief Business OfficerSell5,635$80.16
Jun 26, 2026Monia Brett Pdirector, officer: Chief Executive OfficerOption21,072$32.60
Jun 26, 2026Monia Brett Pdirector, officer: Chief Executive OfficerOption14,565$32.60
Jun 26, 2026Monia Brett Pdirector, officer: Chief Executive OfficerOption50,000$56.78
Jun 26, 2026Swayze Ericofficer: EVP ResearchSell10,602$79.18
Jun 26, 2026Monia Brett Pdirector, officer: Chief Executive OfficerSell50,000$80.59
Jun 26, 2026Monia Brett Pdirector, officer: Chief Executive OfficerSell21,072$78.49
Jun 26, 2026Monia Brett Pdirector, officer: Chief Executive OfficerSell14,565$78.41
Jun 16, 2026BERTHELSEN SPENCER RdirectorSell8,000$73.49
Jun 16, 2026Kordasiewicz Holly B.officer: EVP, Chief Development OfficerOption19,895$56.78
Jun 16, 2026Kordasiewicz Holly B.officer: EVP, Chief Development OfficerSell41,004$73.09
Jun 16, 2026Kordasiewicz Holly B.officer: EVP, Chief Development OfficerSell19,842$74.05
Jun 16, 2026BERTHELSEN SPENCER RdirectorOption8,000$24.42
Jun 16, 2026Kordasiewicz Holly B.officer: EVP, Chief Development OfficerOption21,000$60.89
Jun 16, 2026Kordasiewicz Holly B.officer: EVP, Chief Development OfficerOption7,951$60.89
Jun 16, 2026Kordasiewicz Holly B.officer: EVP, Chief Development OfficerOption12,000$32.60
Jun 8, 2026Reikes Peter NdirectorGrant10,753$75.13
Jun 8, 2026HANTSON LUDWIGdirectorGrant10,753$75.13
Jun 3, 2026BERTHELSEN SPENCER RdirectorSell8,000$75.67
Jun 3, 2026BERTHELSEN SPENCER RdirectorOption8,000$24.42
May 15, 2026Monia Brett Pdirector, officer: Chief Executive OfficerSell3,220$78.68
May 15, 2026Monia Brett Pdirector, officer: Chief Executive OfficerSell1,316$78.01
May 15, 2026Monia Brett Pdirector, officer: Chief Executive OfficerOption3,220$32.60
May 15, 2026Monia Brett Pdirector, officer: Chief Executive OfficerOption1,316$32.60
May 6, 2026LOSCALZO JOSEPHdirectorOption12,000$40.05

Source: IONS SEC Form 4 filings, latest Jun 30, 2026. For informational purposes only — not investment advice.

Institutional activity (13F)

How institutions changed their IONS positions over the last 6 months (SEC Form 13F).

Increased
364
New positions
175
Reduced
302
Sold out
114
Largest moves
InstitutionActionSharesFiled
FMR LLCIncreased24.6MMay 15, 2026
FMR LLCIncreased24.1MFeb 17, 2026
CAPITAL WORLD INVESTORSIncreased21.2MMay 13, 2026
CAPITAL WORLD INVESTORSIncreased18.0MFeb 11, 2026
VANGUARD GROUP INCReduced16.4MJan 29, 2026
VANGUARD CAPITAL MANAGEMENT LLCNew Position14.2MMay 15, 2026
BLACKROCK, INC.Increased10.6MFeb 12, 2026
BLACKROCK, INC.Reduced10.4MMay 13, 2026
T. ROWE PRICE INVESTMENT MANAGEMENT, INC.Reduced9.1MFeb 19, 2026
VANGUARD PORTFOLIO MANAGEMENT LLCNew Position7.8MMay 8, 2026
WELLINGTON MANAGEMENT GROUP LLPIncreased6.4MMay 15, 2026
WELLINGTON MANAGEMENT GROUP LLPReduced6.3MFeb 17, 2026
T. ROWE PRICE INVESTMENT MANAGEMENT, INC.Reduced6.2MMay 15, 2026
TWO SIGMA INVESTMENTS, LPIncreased5.9MMay 15, 2026
BELLEVUE GROUP AGReduced4.8MFeb 17, 2026

Source: SEC Form 13F filings. For informational purposes only — not investment advice.